There is very little research done on the possible cause of Gastroparesis due to smoking. There is very little correlation between the two but it is said that smoking cessation temporarily accelerates gastric emptying, and decreases in beta suggest that initial-phase gastric emptying accelerates after smoking cessation. The temporary acceleration of gastric emptying after smoking cessation may be involved in the temporary increase in appetite and weight gain seen after smoking cessation.
Heavy cigarette smoking is also a plausible cause since smoking causes damage to the stomach lining. Idiopathic Gastroparesis (Gastroparesis with no known cause) accounts for a third of all chronic cases; it is thought that many of these cases are due to an autoimmune response triggered by an acute viral infection.
Smoking has the potential to cause a multitude of diseases in long term use, and can increase the risk of gastrointestinal cancers. While there is some evidence that smoking may speed up gastric emptying in some people, this must be considered alongside the numerous health consequences associated with smoking.
Smoking is just one of many idiopathic agents that can impair gastric emptying and exacerbate Gastroparesis, such as:
- Alcohol
- Nicotine
- Opioids
- Progesterone
- PPI
- Tricyclic Antidepressants
- Dopamine Agonists
- Clonidine
- Calcium Channel Blockers
- Anticholinergics
References:
https://en.wikipedia.org/wiki/Gastroparesis https://www.mayoclinic.org/diseases-conditions/gastroparesis/diagnosis-treatment/drc-20355792 https://www.gastroparesisclinic.org/index.php?pageId=1192&moduleId=195